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Essentials of Diagnostic Surgical Neuropathology

In recent years, rapid strides have been made in the field of Neuropathology. This has led to significant improvement in diagnosis. Emerging information on the pathology of neoplastic and non-neoplastic brain diseases has also improved diagnostic criteria and classification systems, impacting the management of patients.Essentials of Diagnostic Surgical Neuropathology is the first book on Neuropathology in India that covers the vast subject of Surgical Neuropathology in a concise, point-wise format, making reading and recapitulation easy. The main emphasis of this book is on neoplastic pathology, given the revolutionary changes which have occurred in the understanding of CNS tumors. In addition, the book also explains the pathology of non-neoplastic lesions that need surgical intervention. In current clinical practice, clinicians are increasingly dependent upon holistic histomolecular diagnosis that aids clinical decision making. Since ancillary techniques are a very important component of diagnosis and of the final integrated pathology reports, the book also includes immunohistochemistry and molecular diagnosis especially in the brain tumor section.In addition to this, the book has the following special features which, when presented in its user-friendly format, makes it an invaluable resource:High quality representative coloured photomicrographsImmunoprofile and key molecular genetic alterationsPrognostic factorsThis book will serve as an updated reference manual in Neuropathology for neurosurgeons, neurologists, neuro-oncologists, neuro-radiologists and research scientists. It will also be a useful guide to Neuropathology diagnosis for surgical pathologists.

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Price: 50.99 EUR excl. shipping

Euthanasia: Searching for the Full Story

This open access book has been written by ten Belgian health care professionals, nurses, university professors and doctors specializing in palliative care and ethicists who, together, raise questions concerning the practice of euthanasia. They share their experiences and reflections born out of their confrontation with requests for euthanasia and end-of-life support in a country where euthanasia has been decriminalized since 2002 and is now becoming a trivial topic. Far from evoking any militancy, these stories of life and death present the other side of a reality needs to be evaluated more rigorously. Featuring multidisciplinary perspectives, this though-provoking and original book is intended not only for caregivers but also for anyone who questions the meaning of death and suffering, as well as the impact of a law passed in 2002. Presenting real-world cases and experiences, it highlights the complexity of situations and the consequences of the euthanasia law. This book appeals to palliative care providers, hematologists, oncologists, psychiatrists, nurses and health professionals as well as researchers, academics, policy-makers, and social scientists working in health care. It is also a unique resource for those in countries where the decriminalization of euthanasia is being considered. Sometimes shocking, it focuses on facts and lived experiences to challenge readers and offer insights into euthanasia in Belgium.

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Price: 32.99 EUR excl. shipping

Lung Cancer Screening

Lung cancer is the leading cause of cancer-related death among men and women in the U.S. and worldwide. For many decades, lung cancer was the sole cancer among the deadly four without an evidence-based screening method for decreasing mortality. This changed in November 2011, when findings from the National Lung Cancer Screening Trial showed low-dose lung CT screening was more efficacious in reducing deaths in high-risk individuals than conventional radiography. As such, an ever-increasing number of health organizations now recommend this screening protocol.Lung Cancer Screening by Mark Parker and esteemed VCU Health colleagues, fulfills the dire need for a comprehensive guide explaining the crucial aspects of lung cancer screenings. The first two chapters lay a foundation with discussion of lung cancer epidemiology and risk factors beyond cigarette smoking. Subsequent chapters cover the fundamentals, with clinical pearls on setting up a successful lung cancer screening program, patient eligibility criteria, imaging variances of tumors in the lungs, screening pros and cons, and interpreting/reporting screening results.The evolution and future of lung cancer screeningsDetection and management of unexpected incidental pulmonary and non-pulmonary findingsDiscussion of test cases utilizing the Lung-RADSTM risk-stratifying system for low-dose chest CT screeningsBenefits and potential harms associated with mass lung cancer screening programs including false positive, false negative, and over-diagnosis ratesThis state-of-the-art guide is essential reading for radiologists, oncologists, pulmonologists, and internists. It is a must-have bookshelf reference for hospital radiology and oncology departments, in particular for those setting up new lung cancer screening programs.

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Price: 47.99 EUR excl. shipping

Essential Cases in Head and Neck Oncology

A case-focused Otolaryngology primer for trainees and practicing clinicians alikeAs disorders of the head and neck continue to become more prevalent, otolaryngologic head and neck surgeons are in greater demand than ever before. Many schools of medicine are integrating Problem-Based Learning (PBL) to help students develop the skills necessary for surgical management of head and neck conditions, yet the selection of guidebooks available to trainee otolaryngologic surgeons is limited.Essential Cases in Head and Neck Oncology uses real-life clinical cases to present clear and up-to-date explanations of treatment strategies for a wide range of cutaneous, salivary gland, and upper aerodigestive tract conditions, including benign and malignant tumors. Written and edited by renowned leaders in the field, and endorsed by the American Head & Neck Society, this essential resource contains full-color photographs, illustrations, and diagrams to better support readers in acquiring, synthesizing, and applying essential skills and knowledge in a clinical context. Its chapters provide detailed coverage of the oral cavity, skull base, trachea, thyroid, larynx, paragangliomas, salivary glands, and more.This textbook also includes:* Covers the full spectrum of head and neck surgeries, including reconstructive procedures* Discusses ethics related to cancer treatments, medical research, and other care issues* Promotes multidisciplinary critical thinking, clinical problem-solving, communication, and collaboration* Helps medical students and trainees evaluate their learning and contextualize their knowledge* Features high-quality images and succinct explanatory text throughoutEssential Cases in Head and Neck Oncology is an indispensable study aid for trainee clinicians, residents, and fellows studying for board certification and other exams, and an excellent reference guide for oncologists, otolaryngologists, surgeons, and other practitioners working in medical oncology, radiation oncology, and oromaxillofacial surgery.

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Price: 125.99 EUR excl. shipping

Emerging Concepts in Neuro-Oncology

Having been a fairly dormant specialty for many decades, in recent years there has been a remarkable increase in activity in Neuro-oncology from basic science through to the clinics. Reflecting this there have been considerable advancements in the understanding of the biology of CNS malignancies which have infirmed the development of many novel and successful therapies. This work aims to bring together the scattered literature on the new concepts in neuro-oncology for the benefit of those in the field. The book moves from concepts in the scientific basis of neuro-oncology, through to modelling techniques and finishing on the translation into clinical practice. Neuro-Oncology is one of the most exciting and rapidly evolving areas of oncology. In recent years there has been a remarkable increase in activity in the field, from basic science through to the clinic. This is reflected by advances in the understanding of the biology of CNS malignancies which have informed the development of novel and successful therapies. In this environment it is essential to facilitate communication and understanding of new ideas and concepts.Emerging Concepts in Neuro-oncology is written with this in mind: to encourage collaboration across traditional boundaries and promote translational research for patient benefit. The book moves from concepts in the scientific basis of neuro-oncology in part one, through models of brain cancer in part two, to emerging concepts in clinical practice in part three, with a focus on translational research.This book will be an essential read for neuroscience researchers, cancer researchers, neurosurgeons and clinical oncologists as well as anyone with an interest in this exciting, dynamic field.

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Price: 66.99 EUR excl. shipping

n of 1

Twenty-five years ago my doctors had no cure for my cancer. So I went on a quest to find my own treatment. This is my story... In 1991, Glenn Sabin was a 28-year-old newlywed diagnosed with chronic lymphocytic leukemia (CLL)-a disease doctors called "uniformly fatal." Treatments could buy him some time and eventually ease his discomfort, but there was no conventional cure. Glenn's prognosis was clear: he was going to die. Although Glenn and his wife, Linda, continued to consult with doctors, cancer specialists and top oncologists, Glenn made a monumental decision: he would become his own health advocate. While he continued to "watch and wait," Glenn would figure out how to stay alive. No one could predict when a large-scale clinical trial would discover a cure for CLL, so Glenn began his own, medically monitored and carefully researched lifestyle changes. He would conduct his own, single patient clinical trial. He would become an "n of 1." Today, Glenn is not only alive, but a 2012 biopsy at Harvard confirmed that his bone marrow contains no leukemic cells. His case is now part of the medical literature. In n of 1, author Glenn Sabin takes readers along his remarkable journey with 'incurable' cancer, where he discovers: No two cancers are exactly alike. Our bodies, minds and diseases are unique, and need to be treated as such. Knowledge and empowerment are your best allies against a life-limiting diagnosis. Lifestyle changes are a powerful way to help prevent, manage and reduce the recurrence of disease-and to improve your quality of life. A strong support system and a clear mind may significantly improve your health. https://www.glennsabin.com Twitter: @GlennSabin LinkedIn: https://www.linkedin.com/in/glennsabin/

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Price: 16.99 EUR excl. shipping

Computational Intelligence in Oncology (eBook, PDF)

This book encapsulates recent applications of CI methods in the field of computational oncology, especially cancer diagnosis, prognosis, and its optimized therapeutics. The cancer has been known as a heterogeneous disease categorized in several different subtypes. According to WHO's recent report, cancer is a leading cause of death worldwide, accounting for over 10 million deaths in the year 2020. Therefore, its early diagnosis, prognosis, and classification to a subtype have become necessary as it facilitates the subsequent clinical management and therapeutics plan. Computational intelligence (CI) methods, including artificial neural networks (ANNs), fuzzy logic, evolutionary computations, various machine learning and deep learning, and nature-inspired algorithms, have been widely utilized in various aspects of oncology research, viz. diagnosis, prognosis, therapeutics, and optimized clinical management. Appreciable progress has been made toward the understanding the hallmarks of cancer development, progression, and its effective therapeutics. However, notwithstanding the extrinsic and intrinsic factors which lead to drastic increment in incidence cases, the detection, diagnosis, prognosis, and therapeutics remain an apex challenge for the medical fraternity. With the advent in CI-based approaches, including nature-inspired techniques, and availability of clinical data from various high-throughput experiments, medical consultants, researchers, and oncologists have seen a hope to devise and employ CI in various aspects of oncology. The main aim of the book is to occupy state-of-the-art applications of CI methods which have been derived from core computer sciences to back medical oncology. This edited book covers artificial neural networks, fuzzy logic and fuzzy inference systems, evolutionary algorithms, various nature-inspired algorithms, and hybrid intelligent systems which are widely appreciated for the diagnosis, prognosis, and optimization of therapeutics of various cancers. Besides, this book also covers multi-omics exploration, gene expression analysis, gene signature identification of cancers, genomic characterization of tumors, anti-cancer drug design and discovery, drug response prediction by means of CI, and applications of IoT, IoMT, and blockchain technology in cancer research.

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Price: 121.95 EUR excl. shipping