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  Preclinical MRI

  Preclinical MRI ab 117.49 € als Taschenbuch: Methods and Protocols. Softcover reprint of the original 1st ed. 2018. Aus dem Bereich: Bücher, Taschenbücher, Naturwissenschaft,

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  • Price: 117.49 EUR excl. shipping
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  Biosimilars

  Erscheinungsdatum: 29.12.2018, Einband: Gebunden, Titelzusatz: Regulatory, Clinical, and Biopharmaceutical Development, AAPS Advances in the Pharmaceutical Sciences Series 34, Auflage: 1/2018, Herausgeber: Hiten J Gutka/Harry Yang/Shefali Kakar, Verlag: Springer Verlag GmbH, Sprache: Englisch, Schlagworte: biologics // chemistry and manufacturing controls (CMC) // preclinical safety // quality by design // therapeutics, Produktform: Gebunden/Hardback, Umfang: XXIII, 709 S., 25 s/w Illustr., 93 farbige Illustr., Seiten: 709, Format: 4.7 x 24.1 x 16.4 cm, Gewicht: 1256 gr, Verkäufer: averdo

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  • Price: 138.69 EUR excl. shipping
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  Evaluation of Drug Candidates for Preclinical Development

  Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing stability, ways to optimize drug formulation, toxicology and toxicokinetics, and more. Readers will understand why absorption-distribution-metabolism-excretion-toxicology (ADMET) is key in drug development. This is an enlightening reference for scientists, medicinal chemists, and others working in drug discovery.Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the "right" drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early drug discovery to improve the assessment of potential drug compounds. Now, Evaluation of Drug Candidates for Preclinical Development provides a complete view and understanding of why absorption-distribution-metabolism-excretion-toxicology (ADMET) plays a pivotal role in drug discovery and development. Encompassing the three major interrelated areas in which optimization and evaluation of drug developability is most critical-pharmacokinetics and drug metabolism, pharmaceutics, and safety assessment-this unique resource encourages integrated thinking in drug discovery. The contributors to this volume: * Cover drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, stability, drug formulation, preclinical safety assessment, toxicology, and toxicokinetics * Address developability issues that challenge pharma companies, moving beyond isolated experimental results * Reveal connections between the key scientific areas that are critical for successful drug discovery and development * Inspire forward-thinking strategies and decision-making processes in preclinical evaluation to maximize the potential of drug candidates to progress through development efficiently and meet the increasing demands of the marketplace Evaluation of Drug Candidates for Preclinical Development serves as an introductory reference for those new to the pharmaceutical industry and drug discovery in particular. It is especially well suited for scientists and management teams in small- to mid-sized pharmaceutical companies, as well as academic researchers and graduate students concerned with the practical aspects related to the evaluation of drug developability.

  • Shop: buecher
  • Price: 146.99 EUR excl. shipping
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  Preclinical MRI

  Preclinical MRI ab 128.49 € als gebundene Ausgabe: Methods and Protocols. 1st ed. 2018. Aus dem Bereich: Bücher, Wissenschaft, Medizin,

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  • Price: 128.49 EUR excl. shipping
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  Preclinical Development Handbook

  Preclinical Development Handbook ab 187.99 € als pdf eBook: Toxicology. Aus dem Bereich: eBooks, Fachthemen & Wissenschaft, Wissenschaften allgemein,

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  • Price: 187.99 EUR excl. shipping
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  Preclinical Development Handbook

  Preclinical Development Handbook ab 188.99 € als pdf eBook: ADME and Biopharmaceutical Properties. Aus dem Bereich: eBooks, Fachthemen & Wissenschaft, Wissenschaften allgemein,

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  • Price: 188.99 EUR excl. shipping
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  Preclinical Manual of Prosthodontics - E-Book

  Preclinical Manual of Prosthodontics - E-Book ab 8.99 € als epub eBook: . Aus dem Bereich: eBooks, Fachthemen & Wissenschaft, Medizin,

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  • Price: 8.99 EUR excl. shipping
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  Preclinical Manual of Prosthodontics- E Book

  Preclinical Manual of Prosthodontics- E Book ab 13.49 € als epub eBook: . Aus dem Bereich: eBooks, Fachthemen & Wissenschaft, Medizin,

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  • Price: 13.49 EUR excl. shipping
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  Biomarkers for Preclinical Alzheimer's Disease

  Biomarkers for Preclinical Alzheimer's Disease ab 101.49 € als Taschenbuch: Softcover reprint of the original 1st ed. 2018. Aus dem Bereich: Bücher, Taschenbücher, Naturwissenschaft,

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  • Price: 101.49 EUR excl. shipping
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  Preclinical Manual of Conservative Dentistry - E-Book

  Preclinical Manual of Conservative Dentistry - E-Book ab 8.99 € als epub eBook: . Aus dem Bereich: eBooks, Fachthemen & Wissenschaft, Medizin,

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  • Price: 8.99 EUR excl. shipping

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